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Editorial


Front Page - Friday, March 31, 2023

Physician explains colorectal cancer, AI connection




Dr. Henry Paik, gastroenterologist at Parkridge Medical Center in Chattanooga. - Photograph provided

The American Cancer Society estimates colorectal cancer will cause 52,550 deaths during 2023.

The good news? The number of Americans diagnosed with the disease has continued to drop since the mid-1980s due in large part to regular screenings that lead to an earlier diagnosis.

However, this downward trend occurs primarily in older adults. Rates of colorectal cancer are increasing annually for people younger than 50, and doctors are now recommending screenings for people who are age 45 and over.

During Colorectal Cancer Awareness Month, Parkridge Medical Center is shining a light on colorectal cancer signs, risk factors and evolving screening recommendations. Dr. Henry Paik, a board-certified gastroenterologist, speaks on behalf of the 275-bed hospital.

What is colorectal cancer?

Colorectal cancer is an umbrella term referring to the specific group of cancers originating in the colon or rectum. It’s the third most common type of cancer in the United States that affects both men and women.

“When we talk about cancer – any type of cancer – we’re talking about a disease that originates in our own cells. It’s not an infection. It’s basically an error that happens in the programming of our own cells that can be triggered by outside influences,” explains Paik.

“The skin that lines our colon must constantly repair itself throughout our life. So, when our colon is exposed to the toxins in pesticides and preservatives, we increase the chances that the cell repair process will experience a mutation, leading to cancer.”

Polyps don’t always indicate cancer

When a cell in the colon experiences an error that makes it keep growing, it becomes a polyp.

“First, it looks like a little bump. Then, it looks like a little mushroom. Then, it looks like a tree, and then it becomes a mass. But initially, it’s not a cancer,” says Paik. “However, if physicians suspect a polyp might have developed cancer, they might call it high-risk or advanced.

For a long time, it was rare for people younger than 50 to develop polyps in the colon.

“In the previous 10 years, we’ve seen that these polyps are starting to show up earlier. This is the reason why the screening age was lowered to 45. We think they’re starting to develop in our 30s, and by age 45, they’re visible. The cells have to grow enough so we can see them.”

Screening is the best defense against colorectal cancer

Colonoscopies, the best screening tool available, are often able to prevent colon cancer.

“This is not surgery; this is a routine test. Patients shouldn’t expect to feel or remember anything from the procedure,” Paik shares.

During a colonoscopy, doctors use a scope to find any abnormalities in the colon. What makes a colonoscopy unique compared to other screening tests is that precancerous polyps can actually be removed during the procedure, essentially preventing cancer down the road.

While preventing colon cancer is the ideal scenario, sometimes doctors do find cancer. But finding cancer during a routine colonoscopy is better for patients than waiting until symptoms occur, as colon cancer is more treatable if discovered early.

“In the vast majority of colon cancers, you don’t have any symptoms until you have a cancer that’s invaded other structures,” says Paik. “So, you don’t need any symptoms to need a colonoscopy at 45.”

Artificial intelligence enhances colonoscopy screenings

Some Parkridge Health hospitals are using artificial intelligence to enhance the detection of precancerous polyps during colonoscopies. The new technology can bolster a physician’s confidence in giving colonoscopy patients a clean bill of health if no polyp is detected.

“This works the same way your iPhone recognizes your face – even if you have makeup or look different,” explains Paik. “I have a camera, and there’s a live video with a software program scanning every single pixel. That software is trying to identify color patterns that are what you’d see in a polyp.”

Polyp skin looks different from normal colon skin, but sometimes these differences are subtle, or there might be stool in the frame. This can prevent the human eye from spotting these subtle differences in the skin. The AI software sidesteps these human oversights.

“The [developers of the] AI [have trained it] with 10,000 pictures of polyps from different patients. As I’m going through your colon, this software is scanning every pixel. If it detects one of those patterns, it beeps,” says Paik. “Doctors then are able to take a closer look and determine if the polyp should be removed.

This AI software is like having two people looking at your colon at the same time. It increases our confidence when telling someone their colonoscopy is normal.”

Signs, symptoms and risk factors

While anyone can get colorectal cancer, certain factors can increase a person’s risk. Some of these, such as lifestyle behaviors, can be controlled, while others can’t. Risk factors for colorectal cancer include:

• Smoking tobacco and alcohol use

• Being sedentary without regular exercise

• Eating certain processed foods or red meats in excess

• Certain backgrounds, such as being an African American or an Ashkenazi Jew

• Inflammatory bowel disease

• Personal or family history of colon cancer or polyps

Paik says personal or family history is a specific risk factor with conditions to consider. People who have a mother, father or siblings who had colon cancer or polyps found when they were younger than 60 should get their colonoscopy at the age of 40 or 10 years younger than the age at which their family member was diagnosed – whichever comes first.

Often, colorectal cancer symptoms can resemble or be mistaken for other common problems.

“The problem is that most every symptom related to colorectal cancer is most likely something else,” says Paik.

Because these signs are often convoluted, it’s important to talk with a doctor if any of these signs and symptoms persist: Bright red, black or tarry blood in stool, change in bowel habits like diarrhea or constipation, consistent fatigue, discomfort in the abdominal area, including bloating or cramps, frequent gas pains, unexpected weight loss, unusually narrow stools.

However, not all colorectal cancers will cause symptoms early, which is why medical screening is the best early detection tool.

Colon screening and treatment

With multiple locations across the Chattanooga area, Parkridge Health offers access to potentially life-saving procedures.

In addition, Parkridge Health is part of the Sarah Cannon Cancer Institute network of hospitals with access to cutting-edge cancer therapies, clinical trials and the latest advancements in surgical oncology care.

To schedule a preventative cancer screening, such as a colonoscopy, reach out to your primary care physician or call Medline at 423 622-6848 for a free physician referral.

Source: Parkridge Health